Theoretical designing of acetylcholine esterase (Ache) inhibitors

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Theoretical Designing of Acetylcholine Esterase (Ache) Inhibitors

Alzheimer’s disease still remains as an untreatable neurological disorder with no successful treatment strategy to prevent or cure or reverse the damage. Globally, AD is 5th major cause of death. Over last three decades, accumulating evidence for Alzheimer’s suggest multiple causes, predominantly the gene make up of affected individuals are altered. Affected individuals suffer from severe loss ...

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Theoretical Designing of Acetylcholine Esterase (AChE) Inhibitors

Alzheimer’s disease still remains as an untreatable neurological disorder with no successful treatment strategy to prevent or cure or reverse the damage. Globally, AD is 5th major cause of death. Over last three decades, accumulating evidence for Alzheimer’s suggest multiple causes, predominantly the gene make up of affected individuals are altered. Affected individuals suffer from severe loss ...

متن کامل

Theoretical Designing of Acetylcholine Esterase (AChE) Inhibitors

Alzheimer’s disease still remains as an untreatable neurological disorder with no successful treatment strategy to prevent or cure or reverse the damage. Globally, AD is 5th major cause of death. Over last three decades, accumulating evidence for Alzheimer’s suggest multiple causes, predominantly the gene make up of affected individuals are altered. Affected individuals suffer from severe loss ...

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Ache Inhibitors On

This study tested the hypothesis that repeated exposure to low levels of sarin, pyridostigmine bromide (PB) or their combination, at doses equivalent to those possibly experienced by veterans of the 1991 Persian Gulf War, could lead to persistent or delayed autonomic effects and thus help to explain the cause of clinical findings in this population. Male Sprague-Dawley rats were treated for 3 w...

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Comparison of persistence rates of acetylcholine-esterase inhibitors in a state Medicaid program

OBJECTIVE To compare levels of persistency between cholinesterase inhibitors (ChEIs) among a Medicaid patient population of older adults. METHODS Survival analysis was used to assess differences in discontinuation between ChEIs (donepezil versus rivastigmine and galantamine), and for difference in patient gender, age, race, and care setting. RESULTS Rates of discontinuation increased from 4...

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ژورنال

عنوان ژورنال: MOJ Bioorganic & Organic Chemistry

سال: 2018

ISSN: 2574-819X

DOI: 10.15406/mojboc.2018.02.00051